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40 , W452W457 (2012)

Anstee is Pro-Vice-Chancellor of the Faculty of Medical Sciences

2008 Feb;102(2):248-55

A decrease in bioenergetic efficiency is double-faced: it may be beneficial to cellular function through the reduction of reactive oxidative species production and the balancing of nutrient availability [272], but it may also contribute to increasing mitochondrial dysfunction and toxicity [273], which couldaccount for a significant proportion of adverse effects of prescription drugs [26]